76 research outputs found

    A Framework for XML-based Integration of Data, Visualization and Analysis in a Biomedical Domain

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    Biomedical data are becoming increasingly complex and heterogeneous in nature. The data are stored in distributed information systems, using a variety of data models, and are processed by increasingly more complex tools that analyze and visualize them. We present in this paper our framework for integrating biomedical research data and tools into a unique Web front end. Our framework is applied to the University of Washington’s Human Brain Project. Specifically, we present solutions to four integration tasks: definition of complex mappings from relational sources to XML, distributed XQuery processing, generation of heterogeneous output formats, and the integration of heterogeneous data visualization and analysis tools

    Apolipoprotein E and Alzheimer’s disease: The influence of apolipoprotein E on amyloid- and other amyloidogenic proteins

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    Score-Consistent Algebraic Optimization of Full-Text Search Queries with GRAFT

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    We address two open problems involving algebraic execution of full-text search queries. First, we show how to correctly apply traditional database rewrite optimizations to full-text algebra plans with integrated scoring, and explain why existing techniques fail. Second, we show how our techniques are applied in a generic scoring framework that supports a wide class of scoring algorithms, including algorithms seen in the literature and user-defined scoring. Categories and Subject Descriptor
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